KHV or CGNV Sleeping Sickness?

On Sat, Apr 13, 2019 at 4:51 PM R. KROUZEL  wrote:
> > Watched your KHV video today. > > Is it possible that the Koi you referred to in your video had ‘Koi > sleeping sickness’ as opposed to KHV? > > Prescribed treatment from Japan for sleeping sickness is 85 F, no food and > 1.006 salt. > > Cheers > > Romana > >

Is it possible that the Koi you referred to in your video had ‘Koi sleeping sickness’ as opposed to KHV? Prescribed treatment from Japan for sleeping sickness is 85 F, no food and 1.006 salt.

ANSWER:

There is an interesting parallel

They can recover a specific virus from the KHV fish that’s not in the Sleeping Sickness ones. And the morbidities / mortalities on KHV are catastrophic in short order, compared to the Sleeping Sickness.

We’re lucky in poikilotherms that we can set the “body temperature” at anything we want – whereas a cat or dog or person with a virus is pretty much stuck in the viruses’ favorite range (once adapted to and infectious for) mammalian cells at 98.6-101.6 So we can take an infectious, lipophilic / heat labile virus (simply melts) to temperatures that destroy the capsule/capsid. (By no means are all viruses heat labile)

I have to admit I’m not very familiar with Koi / Carp Sleeping Sickness because of two things

1) I always wrote Sleeping Sickness off as fulminating stress-response (which may be directly related to vulnerability to a ubiquitous CGNV virus -AND-

2) It has been a nonsequiter in practice because it really does tend to clear as water temperature, water quality and the presence of pathogens are resolved.

Doc Johnson

Koi Herpes Virus Video

Carp Edema Virus Disease (CEVD)_Koi Sleepy Disease