Category Archives: Diagnostics

The diagnostics that may be brought to bear on dog and cat clinical cases.

Cushing’s Disease Veterinary Notes

Cushing’s Disease Veterinary Notes

So, I put together 39 pages of information on Cushing’s Disease, which is overactive Adrenal Glands. The body produces way too much Cortisol and the impact is insulin antagonism, and hunger and thirst, weight gain, thinning skin, premature aging. And increased vulnerability to infections.

Cushings
There are two other resources on DrJohnson.com for HyperAdrenoCorticism

Actually, a lot of the same symptoms (besides thirst and elevated liver enzymes) of Hypo-Thyroidism.

And, so that I don’t look totally stupid when I walk into the exam room with my Cushing’s Cases, I put together THIS DOCUMENT to leaf through over my lunch.

There’s the diagnostic algorithm, and the numbers you want to see, and then treatments are discussed and my favorite (because it hedges itself against Addisonian Crisis) is the Utrecht Method of medicine.

Cushing’s Disease Veterinary Notes

Visit the Cushing’s Book

Mult-Drug-Resistance-1 (MDR-1) Gene in Dogs What Does It Mean?

We sent some samples out for genetic DNA testing on a dog, to find out what breeds he was and one of the tests came back positive for the MDR-1 gene. The owner asked me what that was, and whether it mattered or not.

Mult-Drug-Resistance-1 MDR-1 Gene in Dogs What Does It Mean?

In a nutshell it means that the dog MAY have trouble excreting a drug we might give. That means that things like sedative, loperamide, epilepsy medicine, and other medicines that are heavily processed by the liver for excretion may remain in the system longer than in other dogs.

Sedatives hit harder. Heart medicines stay around longer (and may work better) etc.

Mult-Drug-Resistance-1 (MDR-1) Gene in Dogs What Does It Mean?
Mult-Drug-Resistance-1 (MDR-1) Gene in Dogs What Does It Mean?

I downloaded information on MDR-1 because it explains it, some and also lists some of the drugs that can remain ‘too long’ in these MDR-1 dogs.

Mult-Drug-Resistance-1 MDR-1 Gene in Dogs What Does It Mean?

Mdr1 Collie

MDR1_multi_drug_resistance_one_sheet

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So Your Pet Has Kidney Issues?

Kidney Case Review and Understanding Kidney Disease in Companion Animals

This document is for my clients who have pets that have been diagnosed with kidney issues. There’s a ton of information to take in when you get that ‘news’ and so I put together this one-page handout to refresh your memory after we talk. Interpretation of your pet’s Creatinine levels is of key import. How we manage kidney cases is presented.

https://drjohnson.com/wp-content/uploads/2019/09/Kidney-Cats-and-Dogs.pdf