Zoetis Apoquel Package Insert – Download

Information on the Apoquel cancer ‘thing’ and not ‘hearsay’

Six dogs were euthanized because of suspected malignant neoplasms: including thoracic metastatic, abdominal metastatic, splenic, frontal sinus, and intracranial neoplasms, and transitional cell carcinoma.

Folks want information on the Apoquel cancer ‘thing’ and not ‘hearsay’ so I thought you might like to read the actual package insert.

https://drjohnson.com/wp-content/uploads/2019/09/apoquel_pi.pdf

Second Column

“Two other dogs on APOQUEL were withdrawn from study due to suspected
or confirmed malignant neoplasia and subsequently euthanized, including one dog that developed signs
associated with a heart base mass after 21 days of APOQUEL administration, and one dog that developed
a Grade III mast cell tumor after 60 days of APOQUEL administration. One of the 147 dogs in the placebo
group developed a Grade I mast cell tumor and was withdrawn from the masked study. ”

“Six dogs were euthanized because of suspected malignant neoplasms:
including thoracic metastatic, abdominal metastatic, splenic, frontal sinus, and intracranial neoplasms, and
transitional cell carcinoma after 17, 120, 175, 49, 141, and 286 days of APOQUEL administration, respectively.
Two dogs each developed a Grade II mast cell tumor after 52 and 91 days of APOQUEL administration,
respectively. One dog developed low grade B-cell lymphoma after 392 days of APOQUEL administration.
Two dogs each developed an apocrine gland adenocarcinoma (one dermal, one anal sac) after approximately
210 and 320 days of APOQUEL administration, respectively. One dog developed a low grade oral spindle
cell sarcoma after 320 days of APOQUEL administration. ”

 

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