Assessment of Silybin / Which is Pretty Much “Denamarin” (Of Which I Hold a Low Opinion)

Denamarin was a “me too” veterinary preparation of Milk Thistle sold as a ‘proprietary’ answer to the far-more-effective “Urso” which is ‘ursodehydrocholic acid’ and had been working WELL for liver disease, cirrhotic, fibrotic, infectious….But Veterinarians didn’t ‘control’ the drug and there was a generic.

Milk Thistle contains minuscule amounts of UDCA and so it was a “me too” but didn’t work as well. So I stuck with Urso.

Denamarin contains SILYBIN as well, which is a ‘not-inconvenient’ delivery system for flavonoids. Those are ‘oils’ that can come from various thinks like Palmarosa oil, etc. Except Silybin contains SEVERAL Flavonoids.

So, I went out and found a decent study that performed to HUMAN-level stakes of research quality and reviews of thousands of pieces of literature. Thank god I didn’t have to do it LOLOLOL

Here’s the publication, in it’s entirety and not to decrease the economic value of the original document nor use it in a commercial measure. Fair use.

This document is a records review of numerous human studies on Silybin, the active in Denamarin.

Dr Erik Johnson is a Marietta, Georgia Veterinarian with a practice in small animal medicine. He graduated from University of Georgia with his Doctorate in 1991. Dr Johnson is the author of several texts on Koi and Pond Fish Health and Disease as well as numerous articles on dog and cat health topics.